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3-dodecylthiopropane-1,2-diol

  • Product Name 3-dodecylthiopropane-1,2-diol
  • cas 18023-86-4
  • purity 99%
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Quality manufacturer supply 3-dodecylthiopropane-1,2-diol 18023-86-4 in stock with high standard

  • Molecular Formula: C15H32 O2 S
  • Molecular Weight: 276.484
  • Vapor Pressure: 1.62E-08mmHg at 25°C 
  • Boiling Point: 412.2°C at 760 mmHg 
  • Flash Point: 200.2°C 
  • PSA: 65.76000 
  • Density: 0.968g/cm3 
  • LogP: 3.99370 

3-dodecylthiopropane-1,2-diol(Cas 18023-86-4) Usage

InChI:InChI=1/C15H32O2S/c1-2-3-4-5-6-7-8-9-10-11-12-18-14-15(17)13-16/h15-17H,2-14H2,1H3

18023-86-4 Relevant articles

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Lawson,D.D. et al.

, p. 615 - 616 (1961)

-

Nucleoside Conjugates. 13. Synthesis and Antitumor Activity of 1-β-D-Arabinofuranosylcytosine Conjugates of Thioether Lipids with Improved Water Solubility

Hong, Chung Il,Nechaev, Alexander,Kirisits, Alan J.,Vig, Rakesh,West, Charles R.

, p. 1785 - 1790 (1993)

A series of ara-CDP-rac-1-S-alkyl-2-O-ac...

Thio-ether functionalized glycolipid amphiphilic compounds reveal a potent activator of SK3 channel with vasorelaxation effect

Sevrain, Charlotte M.,Fontaine, Delphine,Bauduin, Alicia,Guéguinou, Maxime,Zhang, Bei Li,Chant?me, Aurélie,Mahéo, Karine,Pasqualin, C?me,Maupoil, Véronique,Couthon, Hélène,Vandier, Christophe,Jaffrès, Paul-Alain

supporting information, p. 2753 - 2766 (2021/04/07)

The modulation of SK3 ion channels can b...

ANTIVIRAL COMPOUNDS AND COMPOSITIONS

-

, (2008/12/08)

Described herein are compounds useful in...

Synthesis and cytotoxic activity of two novel 1-dodecylthio-2-decyloxypropyl-3-phosphatidic acid conjugates with gemcitabine and cytosine arabinoside

Alexander, Richard L.,Morris-Natschke, Susan L.,Ishaq, Khalid S.,Fleming, Ronald A.,Kucera, Gregory L.

, p. 4205 - 4208 (2007/10/03)

Cytosine arabinoside (ara-C) and gemcita...

18023-86-4 Process route

3-monochloro-1,2-propanediol
96-24-2

3-monochloro-1,2-propanediol

1-dodecylthiol
112-55-0

1-dodecylthiol

1-n-dodecylthio-2,3-propanediol
18023-86-4

1-n-dodecylthio-2,3-propanediol

Conditions
Conditions Yield
With sodium hydroxide;
rac-3-sulfanylpropane-1,2-diol
96-27-5

rac-3-sulfanylpropane-1,2-diol

1-dodecylbromide
143-15-7

1-dodecylbromide

1-n-dodecylthio-2,3-propanediol
18023-86-4

1-n-dodecylthio-2,3-propanediol

Conditions
Conditions Yield
rac-3-sulfanylpropane-1,2-diol; With potassium hydroxide; In ethanol; at 20 ℃; for 0.5h;
1-dodecylbromide; In ethanol; at 20 ℃; for 48h;
81%
rac-3-sulfanylpropane-1,2-diol; With potassium hydroxide; In ethanol; at 20 ℃; for 0.5h;
1-dodecylbromide; In ethanol; for 24h;
67.2%
With potassium carbonate; In water; acetone; for 24h; Ambient temperature;
With potassium hydroxide; In hexane; for 48h; Ambient temperature;

18023-86-4 Upstream products

  • 96-24-2
    96-24-2

    3-monochloro-1,2-propanediol

  • 112-55-0
    112-55-0

    1-dodecylthiol

  • 96-27-5
    96-27-5

    rac-3-sulfanylpropane-1,2-diol

  • 143-15-7
    143-15-7

    1-dodecylbromide

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