Factory Sells Best Quality Mitoxantrone hydrochloride 70476-82-3 with GMP standards We provide high quality Mitoxantrone hydrochloride (CAS 70476-82-3), at a very affordable prices to our customers.

1.What is the Mitoxantrone hydrochloride ?

Mitoxantrone is an anthraquinone that intercalates in DNA and inhibits topoisomerase II (IC50 = 5.3 μM), thus inhibiting cell proliferation. It also inhibits HIV-1 integrase (IC50 = 3.8 μM). Mitoxantrone is exported from cells in an ATP- and glutathione-dependent manner by multidrug resistance protein-1. Formulations containing mitoxantrone have been used in the treatment of cancer and multiple sclerosis.

Mitoxantrone dihydrochloride is an antiviral, antibacterial, antiprotozoal, immunomodulating, and antineoplastic cytostatic anthraquinone derivative. Induces DNA damage by intercalating into DNA and inhibiting Topo II (topoisomerase II). Mitoxantrone dihydrochloride induces interstrand DNA cross-links and DNA-protein cross-links in cellular systems. Mitoxantrone dihydrochloride has recently been shown to be an inhibitor of DNA methylation.

2.What is the CAS number for Mitoxantrone hydrochloride ?

The CAS number of Mitoxantrone hydrochloride is 70476-82-3.

More information of Mitoxantrone hydrochloride 70476-82-3 are:

3.What is the molecular formula of Mitoxantrone hydrochloride ?

The chemical formula of?Mitoxantrone hydrochloride is C22H28N4O6. 2HCl which containing 22 Carbon atoms,29 Hydrogen atoms,4 Nitrogen atoms,1 Oxygen atoms and 1 Chlorine atoms,and the molecular weight, and the molecular weight of Mitoxantrone hydrochloride is 517.409

4.What is Mitoxantrone hydrochloride(70476-82-3)used for?

Mitoxantrone is an anthraquinone that intercalates in DNA and inhibits topoisomerase II (IC50 = 5.3 μM), thus inhibiting cell proliferation. It also inhibits HIV-1 integrase (IC50 = 3.8 μM). Mitoxantrone is exported from cells in an ATP- and glutathione-dependent manner by multidrug resistance protein-1. Formulations containing mitoxantrone have been used in the treatment of cancer and multiple sclerosis.

InChI:InChI=1/C22H28N4O6.3ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;;/h1-4,23-30H,5-12H2;3*1H

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5.Factory Sells Best Quality Mitoxantrone hydrochloride 70476-82-3 with GMP standards

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