High Quality Chinese Manufacturer supply 129-56-6 1,9-Pyrazoloanthrone

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1,9-Pyrazoloanthrone

Product Name 1,9-Pyrazoloanthrone
cas 129-56-6
purity 99%

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High Quality Chinese Manufacturer supply 129-56-6 1,9-Pyrazoloanthrone We supply high quality 1,9-Pyrazoloanthrone (CAS 129-56-6), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the 1,9-Pyrazoloanthrone ?

1,9-Pyrazoloanthrone is yellow, while it's Molecular Formula is C14H8N2O. SP 600125 is a Jun N-terminal kinase (JNK) inhibitor.

What is the CAS number for 1,9-Pyrazoloanthrone ?

The CAS number of 1,9-Pyrazoloanthrone is 129-56-6.

More information of 1,9-Pyrazoloanthrone 129-56-6 are:

Synonyms	Anthra[1,9-cd]pyrazol-6(2H)-one;1PMV;2H-Dibenzo[cd,g]indazol-6-one;C.I. 70300;NSC 75890;Pyrazolanthrone;Pyrazoleanthrone;SP 600125;
CAS?Number	129-56-6
Molecular Formula	C14H8N2O
Molecular Weight	220.23
Density	1.463 g/cm³
Melting Point	281~282 °C
Boiling Point	489.28 °C at 760 mmHg
Flash Point	246.787 °C
HS CODE	29339900
PSA	45.75000
LogP	2.66730
Pka	11.75±0.20(Predicted)

What is 1,9-Pyrazoloanthrone (129-56-6) used for?

SP-600125 (129-56-6) is a selective inhibitor of c-Jun N-terminal kinase (JNK). Reversibly inhibits JNK1,2 and 3 (IC50‘s range from 40-90 nM). >300-fold selectivity for JNK as compared to related MAP kinases. Anti-inflammatory activity. SP-600125 inhibits expression of presenilin-1 and Notch signaling in mouse brain. Cell permeable and active in vivo.

InChI:InChI=1/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7H,(H,15,16)

Articles related to 1,9-Pyrazoloanthrone:

Article

Source

Structural and biological evaluation of halogen derivatives of 1,9-pyrazoloanthrones towards the design of a specific potent inhibitor of c-Jun-N-terminal kinase (JNK)

Ganduri, Ramesh,Singh, Vikas,Biswas, Ansuman,Karothu, Durga Prasad,Sekar, Kanagaraj,Balaji, Kithiganahalli N.,Guru Row, Tayur N.

, p. 10651 - 10660 (2018)

Method for producing pyrazolanthone by using 1 - aminoanthraquinone (by machine translation)

Paragraph 0019-0048, (2020/11/10)

How to get the best price on 1,9-Pyrazoloanthrone?

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